Recombinant human MAPRE2 protein
MAPRE2, also known as RP1 or EB2, is evolutionarily conserved proteins, which associate with the tips of growing microtubules, and regulate microtubule dynamics and their interactions with intracellular structures. It has been shown that EB proteins regulate microtubule function through CLIP proteins. Recombinant human MAPRE2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Product Specifications
Product Name Alternative
Microtubule-associated protein RP/EB family member 2, Microtubule-associated protein, RP/EB family member 2, EB1, EB2, RP1
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
39.1 kDa (347aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Renner C., et al. (1997) J. Immunol. 159:1279-1283; ; Bu W., et al. (2003) J. Biol. Chem. 278:49721-49731
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT
Scientific Category
Cytoskeleton
NCBI Accession Number
NP_055083.1
Uniprot Accession Number
Q15555
Species
Human
AA Sequence
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