Recombinant human HSPB3 protein
HSPB3, also known as HSPL27, is a muscle-specific small heat shock protein. It is expressed preferentially in heart and skeletal muscle. Mammalian small heat shock proteins (sHSP) is a abundantly expressed proteins with diverse functions, including the assembly and sequestering of multi-protein complexes, transportation of nascent polypeptide chains across cellular membranes and regulation of protein folding. HSPB3 functions as an ATP-dependent chaperone protein that plays a role in the refolding of denatured proteins and may also Inhibitor of actin polymerization.
Product Specifications
Product Name Alternative
Heat shock protein beta-3, DHMN2C, HMN2C, HSPL27
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
19.1 kDa (170aa)
Additionnal Information
References & Citations
Fontaine JM., et al. (2005) Biochem Biophys Res Commun. 337 (3) :1006-11.; ; Suqiyama Y., et al. (2000) J Biol Chem. 275 (2) :1095-104.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) 5% glycerol, 1M urea.
Scientific Category
Heat Shock Proteins
NCBI Accession Number
NP_006299
Uniprot Accession Number
Q12988
Species
Human
AA Sequence
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