Recombinant human HSPB3 protein

HSPB3, also known as HSPL27, is a muscle-specific small heat shock protein. It is expressed preferentially in heart and skeletal muscle. Mammalian small heat shock proteins (sHSP) is a abundantly expressed proteins with diverse functions, including the assembly and sequestering of multi-protein complexes, transportation of nascent polypeptide chains across cellular membranes and regulation of protein folding. HSPB3 functions as an ATP-dependent chaperone protein that plays a role in the refolding of denatured proteins and may also Inhibitor of actin polymerization.

Product Specifications

Product Name Alternative

Heat shock protein beta-3, DHMN2C, HMN2C, HSPL27

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

19.1 kDa (170aa)

Additionnal Information

HSPB3, Heat shock protein beta-3, DHMN2C, HMN2C, HSPL27, ATGP1202-10 µg, ATGP1202-20 µg, ATGP1202-50 µg, ATGP1202-100 µg, ATGP1202-250 µg, ATGP1202-500 µg, ATGP1202-1 mg, ATGP1202-10, ATGP1202-20, ATGP1202-50, ATGP1202-100, ATGP1202-250, ATGP1202-500, ATGP1202-1

References & Citations

Fontaine JM., et al. (2005) Biochem Biophys Res Commun. 337 (3) :1006-11.; ; Suqiyama Y., et al. (2000) J Biol Chem. 275 (2) :1095-104.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) 5% glycerol, 1M urea.

Scientific Category

Heat Shock Proteins

NCBI Accession Number

NP_006299

Uniprot Accession Number

Q12988

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MAKIILRHLI EIPVRYQEEF EARGLEDCRL DHALYALPGP TIVDLRKTRA AQSPPVDSAA ETPPREGKSH FQILLDVVQF LPEDIIIQTF EGWLLIKAQH GTRMDEHGFI SRSFTRQYKL PDGVEIKDLS AVLCHDGILV VEVKDPVGTK