Recombinant human LOX-1/OLR1 protein
OLR1, also known as oxidized low density lipoprotein (Ox-LDL) receptor 1, is a type II membrane protein that is a member of the C-type lectin family and acts as a cell-surface receptor for Ox-LDL. Ox-LDL plays a role in early ather-osclerosis, which includes the transformation of monocyte-derived macro-phages to foam cells in atherosclerotic lesions. This protein may also trigger the activation of the NFkB signal transduction pathway.
Product Specifications
Product Name Alternative
Oxidized low density lipoprotein (lectin-like) receptor 1, CLEC8A, LOX1, SCARE1
Expression System
E.coli
Antigen Species
Human
Tag
Non-Tagged
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
24.7 kDa (216aa)
Additionnal Information
References & Citations
Kataoka H. et al. (1999) Circulation 99: 3110-3117.; ; Cominacini L. et al. (2000) J. Biol. Chem. 275: 12633-12638.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 5% glycerol, 0.4M urea
Scientific Category
Metabolism
NCBI Accession Number
NP_002534
Uniprot Accession Number
P78380
Species
Human
AA Sequence
Frequently Asked Questions
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