Recombinant human LOX-1/OLR1 protein

OLR1, also known as oxidized low density lipoprotein (Ox-LDL) receptor 1, is a type II membrane protein that is a member of the C-type lectin family and acts as a cell-surface receptor for Ox-LDL. Ox-LDL plays a role in early ather-osclerosis, which includes the transformation of monocyte-derived macro-phages to foam cells in atherosclerotic lesions. This protein may also trigger the activation of the NFkB signal transduction pathway.

Product Specifications

Product Name Alternative

Oxidized low density lipoprotein (lectin-like) receptor 1, CLEC8A, LOX1, SCARE1

Expression System

E.coli

Antigen Species

Human

Tag

Non-Tagged

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

24.7 kDa (216aa)

Additionnal Information

LOX1, OLR1, Oxidized low density lipoprotein (lectin-like) receptor 1, CLEC8A, LOX1, SCARE1, ATGP1199-10 µg, ATGP1199-20 µg, ATGP1199-50 µg, ATGP1199-100 µg, ATGP1199-250 µg, ATGP1199-500 µg, ATGP1199-1 mg, ATGP1199-10, ATGP1199-20, ATGP1199-50, ATGP1199-100, ATGP1199-250, ATGP1199-500, ATGP1199-1

References & Citations

Kataoka H. et al. (1999) Circulation 99: 3110-3117.; ; Cominacini L. et al. (2000) J. Biol. Chem. 275: 12633-12638.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 5% glycerol, 0.4M urea

Scientific Category

Metabolism

NCBI Accession Number

NP_002534

Uniprot Accession Number

P78380

Species

Human

AA Sequence

MQLSQVSDLL TQEQANLTHQ KKKLEGQISA RQQAEEASQE SENELKEMIE TLARKLNEKS KEQMELHHQN LNLQETLKRV ANCSAPCPQD WIWHGENCYL FSSGSFNWEK SQEKCLSLDA KLLKINSTAD LDFIQQAISY SSFPFWMGLS RRNPSYPWLW EDGSPLMPHL FRVRGAVSQT YPSGTCAYIQ RGAVYAENCI LAAFSICQKK ANLRAQ