What is the catalog number for Recombinant human FLIP protein?

The catalog number for Recombinant human FLIP protein is ATGP1195-100.

What sizes are available for Recombinant human FLIP protein?

Recombinant human FLIP protein is available in the following size(s): 100 µg.

Is Recombinant human FLIP protein in stock?

Recombinant human FLIP protein is currently made to order / not held in immediate stock. Contact us for lead time.

Recombinant human FLIP protein

CFLAR, also known as FLIP, is involved in the regulation of apoptosis. It has been designated by independent groups as Casper, I-FLICE, CLARP, FLAME-1 and MRIT. Although its exact role is still being elucidated, it appears to be an important factor in the regulation of apoptosis downstream of all known death receptors. Recombinant human CFLAR protein was expressed in E. coli and denatured using detergent during a conventional chromatography purification process.

Product Specifications

Product Name Alternative

CASP8 and FADD-like apoptosis regulator, CASH, FLIP, MRIT, CLARP, FLAME, Casper, FLAME1, c-FLIP, FLAME-1, I-FLICE, uSuRPIN

Expression System

E.coli

Antigen Species

Human

Tag

Non-Tagged

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

55.3 kDa (480aa)

Additionnal Information

FLIP, CASP8 and FADD-like apoptosis regulator, CASH, FLIP, MRIT, CLARP, FLAME, Casper, FLAME1, c-FLIP, FLAME-1, I-FLICE, uSuRPIN, ATGP1195-10 µg, ATGP1195-20 µg, ATGP1195-50 µg, ATGP1195-100 µg, ATGP1195-250 µg, ATGP1195-500 µg, ATGP1195-1 mg, ATGP1195-10, ATGP1195-20, ATGP1195-50, ATGP1195-100, ATGP1195-250, ATGP1195-500, ATGP1195-1

References & Citations

Hu S. et al. (1997) J Biol Chem. 272: 17255-17257.; ; Thome M. et al. (1997) . Nature 386: 517-521

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Scientific Category

Apoptosis

NCBI Accession Number

NP_003870

Uniprot Accession Number

O15519

Species

Human

AA Sequence

MSAEVIHQVE EALDTDEKEM LLFLCRDVAI DVVPPNVRDL LDILRERGKL SVGDLAELLY RVRRFDLLKR ILKMDRKAVE THLLRNPHLV SDYRVLMAEI GEDLDKSDVS SLIFLMKDYM GRGKISKEKS FLDLVVELEK LNLVAPDQLD LLEKCLKNIH RIDLKTKIQK YKQSVQGAGT SYRNVLQAAI QKSLKDPSNN FRLHNGRSKE QRLKEQLGAQ QEPVKKSIQE SEAFLPQSIP EERYKMKSKP LGICLIIDCI GNETELLRDT FTSLGYEVQK FLHLSMHGIS QILGQFACMP EHRDYDSFVC VLVSRGGSQS VYGVDQTHSG LPLHHIRRMF MGDSCPYLAG KPKMFFIQNY VVSEGQLENS SLLEVDGPAM KNVEFKAQKR GLCTVHREAD FFWSLCTADM SLLEQSHSSP SLYLQCLSQK LRQERKRPLL DLHIELNGYM YDWNSRVSAK EKYYVWLQHT LRKKLILSYT