Recombinant human CRCP protein

CRCP, also known as CGRP-RCP, is an ubiquitous coupling protein for the calcitonin gene-related peptide and adrenomedullin receptors. It modulates ligand responsiveness in a variety of tissues. It has been DNA-directed RNA polymerase activity, catalytic activity and calcitonin receptor activity. Recombinant human CRCP protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Product Specifications

Product Name Alternative

DNA-directed RNA polymerase III subunit RPC9, CGRP-RCP, CGRPRCP, MGC111194, RCP, RCP9

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

19 kDa (168aa) confirmed by MALDI-TOF

Additionnal Information

CRCP, DNA-directed RNA polymerase III subunit RPC9, CGRP-RCP, CGRPRCP, MGC111194, RCP, RCP9, ATGP1194-10 µg, ATGP1194-20 µg, ATGP1194-50 µg, ATGP1194-100 µg, ATGP1194-250 µg, ATGP1194-500 µg, ATGP1194-1 mg, ATGP1194-10, ATGP1194-20, ATGP1194-50, ATGP1194-100, ATGP1194-250, ATGP1194-500, ATGP1194-1

References & Citations

Evans B.N. et al. (2000) J Biol Chem. 275: 31438-31443.; ; Sams A. et al. (1999) Regul. Pept. 85: 67-75.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl,1mM DTT

Scientific Category

Neuroscience

NCBI Accession Number

NP_055293

Uniprot Accession Number

O75575

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MEVKDANSAL LSNYEVFQLL TDLKEQRKES GKNKHSSGQQ NLNTITYETL KYISKTPCRH QSPEIVREFL TALKSHKLTK AEKLQLLNHR PVTAVEIQLM VEESEERLTE EQIEALLHTV TSILPAEPEA EQKKNTNSNV AMDEEDPA