Recombinant human CRCP protein
CRCP, also known as CGRP-RCP, is an ubiquitous coupling protein for the calcitonin gene-related peptide and adrenomedullin receptors. It modulates ligand responsiveness in a variety of tissues. It has been DNA-directed RNA polymerase activity, catalytic activity and calcitonin receptor activity. Recombinant human CRCP protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Product Specifications
Product Name Alternative
DNA-directed RNA polymerase III subunit RPC9, CGRP-RCP, CGRPRCP, MGC111194, RCP, RCP9
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
19 kDa (168aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Evans B.N. et al. (2000) J Biol Chem. 275: 31438-31443.; ; Sams A. et al. (1999) Regul. Pept. 85: 67-75.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl,1mM DTT
Scientific Category
Neuroscience
NCBI Accession Number
NP_055293
Uniprot Accession Number
O75575
Species
Human
AA Sequence
Frequently Asked Questions
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