Recombinant human Ephrin-B1 protein
Ephrin-B1, also known as EFNB1, belongs to the Eph family. Ephrins, which act as ligands for Eph receptors, are cell-surface proteins that fall into two categories, ephrin-A and ephrin-B, based on their structure and function. EFNB1 proteins are transmembrane and have conserved cytoplasmic tyrosine residues that are phosphorylated upon interaction with an EphB receptor. Also, EFNB1 transduces outside-in signals through C-terminal protein interactions that effect integrin-mediated cell attachment and migration. Recombinant human EFNB1 fused to His-tag at N-terminus.
Product Specifications
Product Name Alternative
Ephrin B1, EFNB1, EFL-3, ELK ligand, ELK-L, EPH-related receptor tyrosine kinase ligand 2, LERK-2, EPLG2, craniofrontonasal syndrome, CFNS
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
25.3 kDa (231aa)
Additionnal Information
References & Citations
Nagashima K., et al. (2002) Mol Biol Cell. 13:4231-4242.; ; Kalo M S., et al. (1996) J Biol Chem. 276:38940-38948.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 5% glycerol
Scientific Category
Neuroscience
NCBI Accession Number
NP_004420
Uniprot Accession Number
P98172
Species
Human
AA Sequence
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