Recombinant human Ephrin-B1 protein

Ephrin-B1, also known as EFNB1, belongs to the Eph family. Ephrins, which act as ligands for Eph receptors, are cell-surface proteins that fall into two categories, ephrin-A and ephrin-B, based on their structure and function. EFNB1 proteins are transmembrane and have conserved cytoplasmic tyrosine residues that are phosphorylated upon interaction with an EphB receptor. Also, EFNB1 transduces outside-in signals through C-terminal protein interactions that effect integrin-mediated cell attachment and migration. Recombinant human EFNB1 fused to His-tag at N-terminus.

Product Specifications

Product Name Alternative

Ephrin B1, EFNB1, EFL-3, ELK ligand, ELK-L, EPH-related receptor tyrosine kinase ligand 2, LERK-2, EPLG2, craniofrontonasal syndrome, CFNS

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

25.3 kDa (231aa)

Additionnal Information

Ephrin-B1, Ephrin-B1, CFND, CFNS, EFL3, Elk-L, EPLG2, LERK2, ATGP1193-10 µg, ATGP1193-20 µg, ATGP1193-50 µg, ATGP1193-100 µg, ATGP1193-250 µg, ATGP1193-500 µg, ATGP1193-1 mg, ATGP1193-10, ATGP1193-20, ATGP1193-50, ATGP1193-100, ATGP1193-250, ATGP1193-500, ATGP1193-1

References & Citations

Nagashima K., et al. (2002) Mol Biol Cell. 13:4231-4242.; ; Kalo M S., et al. (1996) J Biol Chem. 276:38940-38948.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 5% glycerol

Scientific Category

Neuroscience

NCBI Accession Number

NP_004420

Uniprot Accession Number

P98172

Species

Human

AA Sequence

LAKNLEPVS WSSLNPKFLS GKGLVIYPKI GDKLDIICPR AEAGRPYEYY KLYLVRPEQA AACSTVLDPN VLVTCNRPEQ EIRFTIKFQE FSPNYMGLEF KKHHDYYITS TSNGSLEGLE NREGGVCRTR TMKIIMKVGQ DPNAVTPEQL TTSRPSKEAD NTVKMATQAP GSRGSLGDSD GKHETVNQEE KSGPGASGGS SGDPDGFFNS K