Recombinant human MYL12A protein

MYL12A, also known as myosin regulatory light chain 12A, plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. This protein implicated in cytokinesis, receptor capping, and cell locomotion. Recombinant human MYL12A protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Product Specifications

Product Name Alternative

Myosin regulatory light chain 12A, MLCB, MRCL3, MRLC3, MYL2B

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

22.4 kDa (195aa) confirmed by MALDI-TOF

Additionnal Information

MYL12A, ATGP1163-10 µg, ATGP1163-20 µg, ATGP1163-50 µg, ATGP1163-100 µg, ATGP1163-250 µg, ATGP1163-500 µg, ATGP1163-1 mg, ATGP1163-10, ATGP1163-20, ATGP1163-50, ATGP1163-100, ATGP1163-250, ATGP1163-500, ATGP1163-1

References & Citations

Grant J.W., et al. (1990) Nucleic Acids Res. 18:5892-5892; ; Yu L.-R., et al. (2007) J. Proteome Res. 6:4150-4162

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 1mM DTT

Scientific Category

Cytoskeleton

NCBI Accession Number

NP_006462

Uniprot Accession Number

P19105

Species

Human

AA Sequence

MSSKRT KTKTKKRPQR ATSNVFAMFD QSQIQEFKEA FNMIDQNRDG FIDKEDLHDM LASLGKNPTD EYLDAMMNEA PGPINFTMFL TMFGEKLNGT DPEDVIRNAF ACFDEEATGT IQEDYLRELL TTMGDRFTDE EVDELYREAP IDKKGNFNYI EFTRILKHGA KDKDD