Recombinant human KLF4 protein

KLF4 is a transcription factor which acts as both an activator and repressor. This protein is expressed principally in erythroid tissues and found predominantly in gut. KLF4 is involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Recombinant human KLF4 protein, fused to His-CaM-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Kruppel-like factor 4, EZF, GKLF

Expression System

E.coli

Antigen Species

Human

Tag

His-Cam Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 80% by SDS-PAGE

Molecular Weight

58.1 kDa (545aa)

Additionnal Information

KLF4, Kruppel-like factor 4, EZF, GKLF, ATGP1145-10 µg, ATGP1145-20 µg, ATGP1145-50 µg, ATGP1145-100 µg, ATGP1145-250 µg, ATGP1145-500 µg, ATGP1145-1 mg, ATGP1145-10, ATGP1145-20, ATGP1145-50, ATGP1145-100, ATGP1145-250, ATGP1145-500, ATGP1145-1

References & Citations

Deborah E., et al. (2000) Nucleic Acids Res. 28 (5) :1106-1113.; ; Janiel M., et al. (1996) J Biol Chem. 271 (33) :20009-20017.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT, 0.1M NaCl.

Scientific Category

Differentiation & Regeneration

NCBI Accession Number

NP_004226

Uniprot Accession Number

O43474

Species

Human

AA Sequence

MAHHHHHHMA DQLTEEQIAE FKEAFSLFDK DGDGTITTKE LGTVMRSLGQ NPTEAELQDM INEVDADGNG TIDFPEFLTM MARKMKDTDS EEEIREAFRV FDKDGNGYIS AAELRHVMTN LGEKLTDEEV DEMIREADID GDGQVNYEEF VQMMTAKGSM AVSDALLPSF STFASGPAGR EKTLRQAGAP NNRWREELSH MKRLPPVLPG RPYDLAAATV ATDLESGGAG AACGGSNLAP LPRRETEEFN DLLDLDFILS NSLTHPPESV AATVSSSASA SSSSSPSSSG PASAPSTCSF TYPIRAGNDP GVAPGGTGGG LLYGRESAPP PTAPFNLADI NDVSPSGGFV AELLRPELDP VYIPPQQPQP PGGGLMGKFV LKASLSAPGS EYGSPSVISV SKGSPDGSHP VVVAPYNGGP PRTCPKIKQE AVSSCTHLGA GPPLSNGHRP AAHDFPLGRQ LPSRTTPTLG LEEVLSSRDC HPALPLPPGF HPHPGPNYPS FLPDQMQPQV PPLHYQELMP PGSCMPEEPK PKRGRRSWPR KRTAT