Recombinant human ATF4 protein
Activating transcription factor 4, also known as ATF4, belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins and CREB-like proteins. ATF4 encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. Recombinant human ATF4 protein, fused to His-Calmodulin tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Activating transcription factor 4, CREB2, TXREB, CREB-2
Expression System
E.coli
Antigen Species
Human
Tag
His-Cam Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
56.6 kDa (510aa)
Additionnal Information
References & Citations
Lin Y S., et al. (1988) Proc Natl Acad Sci. 85:3396-4000.; ; Hoeffler JP., et al. (1988) Science. 242:1430-1433.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol
Scientific Category
Signal Transduction
NCBI Accession Number
NP_001666
Uniprot Accession Number
P18848
Species
Human
AA Sequence
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