Recombinant human AIP protein

Aryl hydrocarbon receptor (AHR) interacting protein, also known as AIP, may play a positive role in AHR-mediated (aromatic hydrocarbon receptor) signaling, possibly by influencing its receptivity for ligand and/or its nuclear targeting. It is a Cellular negative regulator of the hepatitis B virus (HBV) X protein. Also, AIP is a ubiquitously expressed protein, binds to HSP 90 and AHR through a highly conserved carboxy-terminal tetraticopeptide repeat domain. Recombinant human AIP protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

AH receptor-interacting protein, Aryl-hydrocarbon receptor-interacting protein, HBV X-associated protein 2, XAP-2, Immunophilin homolog ARA9, Aryl hydrocarbon receptor-associated protein 9, FKBP16, FKBP prolyl isomerase 16, FK506-binding protein 37, FKBP37

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

39.8 kDa (350aa) confirmed by MALDI-TOF

Additionnal Information

AIP, Aryl hydrocarbon receptor interacting protein, ARA9, FKBP37, XAP2, ATGP1137-10 µg, ATGP1137-20 µg, ATGP1137-50 µg, ATGP1137-100 µg, ATGP1137-250 µg, ATGP1137-500 µg, ATGP1137-1 mg, ATGP1137-10, ATGP1137-20, ATGP1137-50, ATGP1137-100, ATGP1137-250, ATGP1137-500, ATGP1137-1

References & Citations

Kazlauskas A., et al. (2000) J Biol Chem. 275:41317-41324.; ; Meyer BK., et al. (1998) Mol Cell Biol. 18:978-988.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol

Scientific Category

Signal Transduction

NCBI Accession Number

AAI04828

Uniprot Accession Number

O00170

Species

Human

AA Sequence

MADIIARLRE DGIQKRVIQE GRGELPDFQD GTKATFHYRT LHSDDEGTVL DDSRARGKPM ELIIGKKFKL PVWETIVCTM REGEIAQFLC DIKHVVLYPL VAKSLRNIAV GKDPLEGQRH CCGVAQMREH SSLGHADLDA LQQNPQPLIF HMEMLKVESP GTYQQDPWAM TDEEKAKAVP LIHQEGNRLY REGHVKEAAA KYYDAIACLK NLQMKEQPGS PEWIQLDKQI TPLLLNYCQC KLVVEEYYEV LDHCSSILNK YDDNVKAYFK RGKAHAAVWN AQEAQADFAK VLELDPALAP VVSRELRALE ARIRQKDEED KARFRGIFSH