Recombinant human Sulfotransferase 1A2/SULT1A2 protein
Sulfotransferase 1A2, also known as SuLT1A2, is a member of sulfotransferase family. Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. It mediates the metabolic activation of carcinogenic N-hydroxyarylamines to DNA binding products and could so participate as modulating factor of cancer risk. Recombinant human SuLT1A2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques
Product Specifications
Product Name Alternative
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
36.4 kDa (315aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Weinshilboum R M., et al. (1997) FASEB J. 11 (1) :3-14.; ; Carlini E J., et al. (2001) Pharmacogenetics. 11 (1) :57-68.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 0.1M NaCl
Scientific Category
Metabolism
NCBI Accession Number
NP_001045
Uniprot Accession Number
P50226
Species
Human
AA Sequence
Frequently Asked Questions
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