Recombinant human Omentin/ITLN1 protein

ITLN1, also known as intelectin1 or omentin, has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. ITLN1 may play a role in the defense system against microorganisms and specifically recognize carbohydrate chains of pathogens and bacterial components containing galactofuranosyl residues, in a calcium-dependent manner.

Product Specifications

Product Name Alternative

Intelectin-1, Endothelial lectin HL-1, Galactofuranose-binding lectin, Intestinal lactoferrin receptor, Omentin, INTL, ITLN, LFR

Expression System

E.coli

Antigen Species

Human

Tag

Non-Tagged

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

33.2 kDa (298aa)

Additionnal Information

Endothelial lectin HL 1, Endothelial lectin HL-1, Galactofuranose binding lectin, Galactofuranose-binding lectin, hIntL, HL 1, HL1, HL-1, Intelectin 1, Intelectin1, Intelectin-1, Intestinal lactoferrin receptor, INTL, ITLN, LFR, Omentin, ATGP1125-10 µg, ATGP1125-20 µg, ATGP1125-50 µg, ATGP1125-100 µg, ATGP1125-250 µg, ATGP1125-500 µg, ATGP1125-1 mg, ATGP1125-010, ATGP1125-020, ATGP1125-050, ATGP1125-100, ATGP1125-250, ATGP1125-500, ATGP1125-01M

References & Citations

Tsuji S., et al. (2001) J. Biol. Chem. 276:23456-23463.; ; Tsuji S., et al. (2007) Glycobiology (10) :1045-51

Other References

Watanabe T, et al. Expression of intelectin-1 in bronchial epithelial cells of asthma is correlated with T-helper 2 (Type-2) related parameters and its function. (Allergy Asthma Clin Immunol. 2017) {https://pubmed.ncbi.nlm.nih.gov/28775743/}

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Scientific Category

Metabolism

NCBI Accession Number

NP_060095

Uniprot Accession Number

Q8WWA0

Species

Human

AA Sequence

MWSTDEANTY FKEWTCSSSP SLPRSCKEIK DECPSAFDGL YFLRTENGVI YQTFCDMTSG GGGWTLVASV HENDMRGKCT VGDRWSSQQG SKAVYPEGDG NWANYNTFGS AEAATSDDYK NPGYYDIQAK DLGIWHVPNK SPMQHWRNSS LLRYRTDTGF LQTLGHNLFG IYQKYPVKYG EGKCWTDNGP VIPVVYDFGD AQKTASYYSP YGQREFTAGF VQFRVFNNER AANALCAGMR VTGCNTEHHC IGGGGYFPEA SPQQCGDFSG FDWSGYGTHV GYSSSREITE AAVLLFYR