Recombinant human CINP protein

CINP, also known as Cyclin-dependent kinase 2-interacting protein, belongs to the CINP family. This protein interacts with the components of the replication complex and 2 kinases, CDK2 and CDC7, thereby providing a functional and physical link between CDK2 and CDC7 during firing of the origins of replication. Recombinant human CINP protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Product Specifications

Product Name Alternative

Cyclin-dependent kinase 2-interacting protein, CDK2-interacting protein

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

26.4 kDa (232aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

Additionnal Information

CINP, Cyclin-dependent kinase 2-interacting protein, CDK2-interacting protein, ATGP1118-10 µg, ATGP1118-20 µg, ATGP1118-50 µg, ATGP1118-100 µg, ATGP1118-250 µg, ATGP1118-500 µg, ATGP1118-1 mg, ATGP1118-10, ATGP1118-20, ATGP1118-50, ATGP1118-100, ATGP1118-250, ATGP1118-500, ATGP1118-1

References & Citations

Grishina I., et al. (2005) Cell Cycle. 4:1120-1126; ; Lovejoy C.A., et al. (2009) Proc. Natl. Acad. Sci. u.S.A. 106:19304-19309

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT

Scientific Category

Cell Cycle

NCBI Accession Number

NP_116019

Uniprot Accession Number

Q9BW66

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MEAKTLGTVT PRKPVLSVSA RKIKDNAADW HNLILKWETL NDAGFTTANN IANLKISLLN KDKIELDSSS PASKENEEKV CLEYNEELEK LCEELQATLD GLTKIQVKME KLSSTTKGIC ELENYHYGEE SKRPPLFHTW PTTHFYEVSH KLLEMYRKEL LLKRTVAKEL AHTGDPDLTL SYLSMWLHQP YVESDSRLHL ESMLLETGHR AL