Recombinant human BST-2/Tetherin protein

BST2, also known as bone marrow stromal antigen 2, is involved in the growth and development of B-cells. BST2 is a human cellular protein which inhibits retrovirus infection by preventing the diffusion of virus particles after budding from infected cells. Initially discovered as an inhibitor to HIV-1 infection in the absence of Vpu, tetherin has also been shown to inhibit the release of other viruses such as the Lassa and Marburg virions. Also, this protein may play a role in B-cell activation in rheumatoid arthritis. Recombinant human BST2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Product Specifications

Product Name Alternative

Bone marrow stromal antigen 2, HM1.24 antigen, Tetherin, CD317

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 80% by SDS-PAGE

Molecular Weight

14.8 kDa (133aa) confirmed by MALDI-TOF

Additionnal Information

BST2, Tetherin, Bone marrow stromal antigen 2, HM1.24 antigen, Tetherin, CD317, ATGP1117-10 µg, ATGP1117-20 µg, ATGP1117-50 µg, ATGP1117-100 µg, ATGP1117-250 µg, ATGP1117-500 µg, ATGP1117-1 mg, ATGP1117-10, ATGP1117-20, ATGP1117-50, ATGP1117-100, ATGP1117-250, ATGP1117-500, ATGP1117-1