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Recombinant human PPBP/CXCL7 protein

PPBP, also known as chemokine (C-X-C motif) ligand 7 (CXCL7), is a platelet-derived growth factor that belongs to the alpha-chemokine family, It is a protein that is released in large amounts from platelets following their activation. It stimulates various processes including mitogenesis, synthesis of extracellular matrix, glucose metabolism and synthesis of plasminogen activator. Recombinant human PPBP protein was expressed in E. coli and purified by using conventional chromatograph.

Product Specifications

Product Name Alternative

Pro-platelet basic protein, Platelet basic protein, PBP, C-X-C motif chemokine 7, Leukocyte-derived growth factor, LDGF, Macrophage-derived growth factor, MDGF, Small-inducible cytokine B7, THBGB1, beta-thromboglobulin, Connective tissue-activating peptide III, Neutrophil-activating peptide-2, SCYB7, TGB, NAP-2-L1, LA-PF4, LDGF, Beta-TG, CTAP3, CXCL7, b-TG1, TGB1, CTAPIII, NAP-2

Expression System

E.coli

Antigen Species

Human

Tag

Non-Tagged

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by BCA assay)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Molecular Weight

10.3 kDa (95aa) confirmed by MALDI-TOF

Additionnal Information

CXCL7, NAP2, Pro-platelet basic protein, B-TG1, Beta-TG, CTAP3, CXCL7, LA-PF4, LDGF, MDGF, NAP-2, PBP, SCYB7, TC1, TGB, THBGB, nap2b-TG1, Beta-TG, beta-thromboglobulin, connective tissue-activating peptide III, CTAPIII, CXCL7, NAP-2-L1, neutrophil-activating peptide 2, platelet basic protein, TGB1, ATGP1109-10 µg, ATGP1109-20 µg, ATGP1109-50 µg, ATGP1109-100 µg, ATGP1109-250 µg, ATGP1109-500 µg, ATGP1109-1 mg, ATGP1109-10, ATGP1109-20, ATGP1109-50, ATGP1109-100, ATGP1109-250, ATGP1109-500, ATGP1109-1

References & Citations

Majumdar S., et al. (1991) J Biol Chem. 266:5785-9.; ; Holt J.C., et al. (1986) Biochemistry 25: 1988-1996.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Scientific Category

Hormones & Cytokines

NCBI Accession Number

NP_002695.1

Uniprot Accession Number

P02775

Species

Human

AA Sequence

MSSTKGQTKR NLAKGKEESL DSDLYAELRC MCIKTTSGIH PKNIQSLEVI GKGTHCNQVE VIATLKDGRK ICLDPDAPRI KKIVQKKLAG DESAD

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