Recombinant human RAB17 protein

RAB17, also known as Ras-related protein Rab17, belongs to the small GTPase superfamily, Rab GTPases are localized to various intracellular compartments and are known to play important regulatory roles in membrane trafficking. It is regulated traffic through the apical recycling endosome, suggested function in polarized sorting in epithelial cells. Recombinant human RAB17 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Product Specifications

Product Name Alternative

Ras-related protein Rab-17, FLJ12538, RAB17 member RAS oncogene family

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

25.6 kDa (232aa) confirmed by MALDI-TOF

Additionnal Information

RAB17, Ras-related protein Rab-17, FLJ12538, ATGP1108-10 µg, ATGP1108-20 µg, ATGP1108-50 µg, ATGP1108-100 µg, ATGP1108-250 µg, ATGP1108-500 µg, ATGP1108-1 mg, ATGP1108-10, ATGP1108-20, ATGP1108-50, ATGP1108-100, ATGP1108-250, ATGP1108-500, ATGP1108-1

References & Citations

Hunziker W. et al. (1998) J Biol Chem. 273:15734-41; ; Zacchi P. et al. (1998) J Cell Biol. 140:1039-53

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 30% glycerol, 0.1M NaCl,1mM DTT

Scientific Category

Signal Transduction

NCBI Accession Number

NP_071894

Uniprot Accession Number

Q9H0T7

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MAQAHRTPQP RAAPSQPRVF KLVLLGSGSV GKSSLALRYV KNDFKSILPT VGCAFFTKVV DVGATSLKLE IWDTAGQEKY HSVCHLYFRG ANAALLVYDI TRKDSFLKAQ QWLKDLEEEL HPGEVLVMLV GNKTDLSQER EVTFQEGKEF ADSQKLLFME TSAKLNHQVS EVFNTVAQEL LQRSDEEGQA LRGDAAVALN KGPARQAKCC AH