Recombinant human RAB3A protein

Rab3A belongs to the small GTPase superfamily, Rab family. It is a small, Ras-like GTPase expressed in neuroendocrine cells, in which it is associated with secretory vesicle membranes and regulates exocytosis. This protein could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal. Recombinant human RAB3A protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

RAB3A member RAS oncogene family, Ras-related protein Rab-3A, RAS-associated protein RAB3A

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

27.1 kDa (240aa) confirmed by MALDI-TOF

Additionnal Information

RAB3A, Ras-related protein Rab-3A, RAB3A, member RAS oncogene family, ATGP1105-10 µg, ATGP1105-20 µg, ATGP1105-50 µg, ATGP1105-100 µg, ATGP1105-250 µg, ATGP1105-500 µg, ATGP1105-1 mg, ATGP1105-10, ATGP1105-20, ATGP1105-50, ATGP1105-100, ATGP1105-250, ATGP1105-500, ATGP1105-1

References & Citations

Brondyk WH. et al. (1995) Mol Cell Biol.15:1137-1143.; ; Novick P. et al. (1993) Cell. 75:597-601.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl,1mM DTT

Scientific Category

Signal Transduction

NCBI Accession Number

NP_002857

Uniprot Accession Number

P20336

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MASATDSRYG QKESSDQNFD YMFKILIIGN SSVGKTSFLF RYADDSFTPA FVSTVGIDFK VKTIYRNDKR IKLQIWDTAG QERYRTITTA YYRGAMGFIL MYDITNEESF NAVQDWSTQI KTYSWDNAQV LLVGNKCDME DERVVSSERG RQLADHLGFE FFEASAKDNI NVKQTFERLV DVICEKMSES LDTADPAVTG AKQGPQLSDQ QVPPHQDCAC