Recombinant human RAB3A protein
Rab3A belongs to the small GTPase superfamily, Rab family. It is a small, Ras-like GTPase expressed in neuroendocrine cells, in which it is associated with secretory vesicle membranes and regulates exocytosis. This protein could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal. Recombinant human RAB3A protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
RAB3A member RAS oncogene family, Ras-related protein Rab-3A, RAS-associated protein RAB3A
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
27.1 kDa (240aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Brondyk WH. et al. (1995) Mol Cell Biol.15:1137-1143.; ; Novick P. et al. (1993) Cell. 75:597-601.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl,1mM DTT
Scientific Category
Signal Transduction
NCBI Accession Number
NP_002857
Uniprot Accession Number
P20336
Species
Human
AA Sequence
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