Recombinant human RAB4A protein

RAB4A belongs to the small GTPase superfamily. RAB4A has been shown to interact with STX4, RAB11FIP1, RABEP1, CD2AP and KIF3B. Rab4 is also involved in the translocation of glucose transporter (Glu4) in adipocytes in response to insulin. Overexpression of Rab4 causes a redistribution of receptors on plasma membrane versus endocytic compartments. Recombinant human RAB4A protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Product Specifications

Product Name Alternative

Ras-related protein Rab-4A, HRES-1/RAB4, RAB4, RAB4A member RAS oncogene family

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

26.5 kDa (238aa) confirmed by MALDI-TOF

Additionnal Information

RAB4A, Ras-related protein Rab-4A, HRES-1/RAB4, RAB4, ATGP1104-10 µg, ATGP1104-20 µg, ATGP1104-50 µg, ATGP1104-100 µg, ATGP1104-250 µg, ATGP1104-500 µg, ATGP1104-1 mg, ATGP1104-10, ATGP1104-20, ATGP1104-50, ATGP1104-100, ATGP1104-250, ATGP1104-500, ATGP1104-1

References & Citations

Li L. et al. (2001) J Biol Chem. 276:5265-73.; ; Lindsay AJ.. et al. (2002) J Biol Chem. 277:12190-9.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol 0.1M NaCl,1mM DTT

Scientific Category

Cancer

NCBI Accession Number

NP_004569

Uniprot Accession Number

P20338

Species

Human

AA Sequence

MSQTAMSETY DFLFKFLVIG NAGTGKSCLL HQFIEKKFKD DSNHTIGVEF GSKIINVGGK YVKLQIWDTA GQERFRSVTR SYYRGAAGAL LVYDITSRET YNALTNWLTD ARMLASQNIV IILCGNKKDL DADREVTFLE ASRFAQENEL MFLETSALTG ENVEEAFVQC ARKILNKIES GELDPERMGS GIQYGDAALR QLRSPRRAQA PNAQECGC