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Recombinant human SNX3 protein

Sorting nexin 3 (SNX3), also known as SDP3, is a member of the large family of hydrophilic proteins that interact with a variety of receptor types and are involved in intracellular trafficking. This protein interacts with phosphatidylinositol-3-phosphate, and is involved in protein trafficking. SNX3 comprises a distinct subgroup of nexins that share less sequence similarity outside of the PX domain and have dramatically different binding affinities for the tyrosine kinase receptors. Recombinant human SNX3 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Sorting nexin 3, SDP3

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

20.9 kDa (182aa) confirmed by MALDI-TOF

Additionnal Information

SNX3, Sorting nexin 3, SDP3, ATGP1101-10 µg, ATGP1101-20 µg, ATGP1101-50 µg, ATGP1101-100 µg, ATGP1101-250 µg, ATGP1101-500 µg, ATGP1101-1 mg, ATGP1101-10, ATGP1101-20, ATGP1101-50, ATGP1101-100, ATGP1101-250, ATGP1101-500, ATGP1101-1

References & Citations

Horazdovsky B F., et al. (1997) Mol Biol Cell. 8:1529-1542.; ; Haft C R., et al. (1998) Mol Biol Cell. 18:7278-7287.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% glycerol, 0.1M NaCl

Scientific Category

Signal Transduction

NCBI Accession Number

NP_003786

Uniprot Accession Number

O60493

Species

Human

AA Sequence

MAETVADTRR LITKPQNLND AYGPPSNFLE IDVSNPQTVG VGRGRFTTYE IRVKTNLPIF KLKESTVRRR YSDFEWLRSE LERESKVVVP PLPGKAFLRQ LPFRGDDGIF DDNFIEERKQ GLEQFINKVA GHPLAQNERC LHMFLQDEII DKSYTPSKIR HA
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