Recombinant human SNX3 protein
Sorting nexin 3 (SNX3), also known as SDP3, is a member of the large family of hydrophilic proteins that interact with a variety of receptor types and are involved in intracellular trafficking. This protein interacts with phosphatidylinositol-3-phosphate, and is involved in protein trafficking. SNX3 comprises a distinct subgroup of nexins that share less sequence similarity outside of the PX domain and have dramatically different binding affinities for the tyrosine kinase receptors. Recombinant human SNX3 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Sorting nexin 3, SDP3
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
20.9 kDa (182aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Horazdovsky B F., et al. (1997) Mol Biol Cell. 8:1529-1542.; ; Haft C R., et al. (1998) Mol Biol Cell. 18:7278-7287.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% glycerol, 0.1M NaCl
Scientific Category
Signal Transduction
NCBI Accession Number
NP_003786
Uniprot Accession Number
O60493
Species
Human
AA Sequence
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