Recombinant human AG-3 protein

AGR3, also known as anterior gradient protein 3 homolog precursor, is a secreted cytoplasmic protein which is involved in metastasis induction and p53 tumour supressor inhibition. It may serve as molecular marker and potential therapeutic target for hormone-responsive breast tumours. Recombinant human AGR3 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Product Specifications

Product Name Alternative

Anterior gradient protein 3 homolog, AG3, BCMP11, hAG-3, HAG3, PDIA18

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

19.5 kDa (169aa) confirmed by MALDI-TOF

Additionnal Information

AG3, Anterior gradient protein 3 homolog, AG3, BCMP11, hAG-3, HAG3, PDIA18, ATGP1096-10 µg, ATGP1096-20 µg, ATGP1096-50 µg, ATGP1096-100 µg, ATGP1096-250 µg, ATGP1096-500 µg, ATGP1096-1 mg, ATGP1096-10, ATGP1096-20, ATGP1096-50, ATGP1096-100, ATGP1096-250, ATGP1096-500, ATGP1096-1

References & Citations

Fletcher G.C., et al. (2003) Br. J. Cancer. 88:579-585; ; Clark H.F., et al. (2003) Arch. Biochem. Genome Res. 13:2265-2270

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT

Scientific Category

Cancer

NCBI Accession Number

NP_789783

Uniprot Accession Number

Q8TD06

Species

Human

AA Sequence

MIAIKKE KRPPQTLSRG WGDDITWVQT YEEGLFYAQK SKKPLMVIHH LEDCQYSQAL KKVFAQNEEI QEMAQNKFIM LNLMHETTDK NLSPDGQYVP RIMFVDPSLT VRADIAGRYS NRLYTYEPRD LPLLIENMKK ALRLIQSEL