Recombinant human TXNL4B protein

TXNL4B, also known as Dim2 or DLP, belongs to the DIM1 family that plays an essential role in pro-mRNA splicing. TXNL4B is required in cell cycle progression for S/G2 transition and interact with PRPF6 subunit of the spliceosome. Recombinant human TXNL4B protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Thioredoxin-like 4B, Dim2, DLP, FLJ20511

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

21.1 kDa (185aa) confirmed by MALDI-TOF

Additionnal Information

TXNL4B, thioredoxin-like 4B, Dim2, DLP, FLJ20511, ATGP1090-10 µg, ATGP1090-20 µg, ATGP1090-50 µg, ATGP1090-100 µg, ATGP1090-250 µg, ATGP1090-500 µg, ATGP1090-1 mg, ATGP1090-10, ATGP1090-20, ATGP1090-50, ATGP1090-100, ATGP1090-250, ATGP1090-500, ATGP1090-1

References & Citations

Sun X., et al. (2004) J Biol Chem 279 (31) : 32839-47.; ; Zhang YZ., et al. (2001) Physiol. Genomics 1 (3) : 109-18.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 30% glycerol, 100 mM NaCl

Scientific Category

Cell Cycle

NCBI Accession Number

NP_060323

Uniprot Accession Number

Q9NX01

Species

Human

AA Sequence

MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMSFL LPKLTSKKEV DQAIKSTAEK VLVLRFGRDE DPVCLQLDDI LSKTSSDLSK MAAIYLVDVD QTAVYTQYFD ISYIPSTVFF FNGQHMKVDY GSPDHTKFVG SFKTKQDFID LIEVIYRGAM RGKLIVQSPI DPKNIPKYDL LYQDI