Recombinant human TXNL4B protein
TXNL4B, also known as Dim2 or DLP, belongs to the DIM1 family that plays an essential role in pro-mRNA splicing. TXNL4B is required in cell cycle progression for S/G2 transition and interact with PRPF6 subunit of the spliceosome. Recombinant human TXNL4B protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Thioredoxin-like 4B, Dim2, DLP, FLJ20511
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
21.1 kDa (185aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Sun X., et al. (2004) J Biol Chem 279 (31) : 32839-47.; ; Zhang YZ., et al. (2001) Physiol. Genomics 1 (3) : 109-18.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 30% glycerol, 100 mM NaCl
Scientific Category
Cell Cycle
NCBI Accession Number
NP_060323
Uniprot Accession Number
Q9NX01
Species
Human
AA Sequence
Frequently Asked Questions
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