Recombinant mouse S100A8 protein

S100A8, also known MRP8, is a member of the S100 family, EF-hand superfamily of calcium binding proteins. This protein is localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. It functions both intracellularly and extracellularly, where it binds to RAGE and CD36. Altered expression of this protein is associated with the disease cystic fibrosis. Recombinant mouse S100A8 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Product Specifications

Product Name Alternative

Protein S100-A8, 60B8Ag, AI323541, B8Ag, Caga, CFAg, CP-10, MRP8, p8

Expression System

E.coli

Antigen Species

Mouse

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

12.4 kDa (109aa) confirmed by MALDI-TOF

Additionnal Information

S100A8, Protein S100-A8, 60B8Ag, AI323541, B8Ag, Caga, CFAg, CP-10, MRP8, p8, ATGP1085-10 µg, ATGP1085-20 µg, ATGP1085-50 µg, ATGP1085-100 µg, ATGP1085-250 µg, ATGP1085-500 µg, ATGP1085-1 mg, ATGP1085-10, ATGP1085-20, ATGP1085-50, ATGP1085-100, ATGP1085-250, ATGP1085-500, ATGP1085-1

References & Citations

Kerkhoff C., et al. (1999) Biochim. Biophys. 1448 (2) :200-11. ; ; Nacken W., et al. (2003) Biochim. Biophys. 60 (6) :569-80.

Other References

Takagi R, et al. S100A9 Increases IL-6 and RANKL Expressions through MAPKs and STAT3 Signaling Pathways in Osteocyte-Like Cells. (Biomed Res Int. 2020) {https://pubmed.ncbi.nlm.nih.gov/32149126/}