Recombinant human Sulfotransferase 2A1/SULT2A1 protein

SuLT2A1, also known dehydroepiandrosterone sulphotransferase, belongs to the sulfotransferase family. This protein is mainly expressed in liver and adrenal tissues, and to a lesser extent in kidney. It catalyzes the 3'-phosphoadenosine 5'-phosphosulfate-dependent sulfation of a wide variety of steroids in human liver and adrenal tissues, and is also responsible for most of the sulfation of bile acids in human liver. Recombinant human SuLT2A1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Product Specifications

Product Name Alternative

Sulfotransferase family 2A member 1, ST2A1, Cytosolic sulfotransferase family 2A, Bile salt sulfotransferase, Dehydroepiandrosterone sulfotransferase, DHEA-ST, DHEA-ST8, Hydroxysteroid Sulfotransferase, HST, ST2, SULT2A3, STD

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

35.9 kDa (305aa) confirmed by MALDI-TOF

Additionnal Information

SULT2A1, Bile salt sulfotransferase, DHEA-ST, DHEAS, HST, hSTa, ST2, ST2A1, ST2A3, ATGP1083-10 µg, ATGP1083-20 µg, ATGP1083-50 µg, ATGP1083-100 µg, ATGP1083-250 µg, ATGP1083-500 µg, ATGP1083-1 mg, ATGP1083-10, ATGP1083-20, ATGP1083-50, ATGP1083-100, ATGP1083-250, ATGP1083-500, ATGP1083-1

References & Citations

Otterness D.M. et al. (1992) Mol. Pharmacol. 41: 865-872.; ; Comer K.A. et al. (1993) Biochem. J. 289: 233-240.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl,1mM DTT

Scientific Category

Cancer

NCBI Accession Number

NP_003158

Uniprot Accession Number

Q06520

Species

Human

AA Sequence

MSDDFLWFEG IAFPTMGFRS ETLRKVRDEF VIRDEDVIIL TYPKSGTNWL AEILCLMHSK GDAKWIQSVP IWERSPWVES EIGYTALSET ESPRLFSSHL PIQLFPKSFF SSKAKVIYLM RNPRDVLVSG YFFWKNMKFI KKPKSWEEYF EWFCQGTVLY GSWFDHIHGW MPMREEKNFL LLSYEELKQD TGRTIEKICQ FLGKTLEPEE LNLILKNSSF QSMKENKMSN YSLLSVDYVV DKAQLLRKGV SGDWKNHFTV AQAEDFDKLF QEKMADLPRE LFPWE