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Recombinant human S100A3 protein

S100A3 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100A3 binds calcium with low affinity and zinc with high affinity and is believed to play a role in the calcium-dependent differentiation of cuticle cells and in the formation of hair shafts. Recombinant human S100A3 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

S100 calcium binding protein A3, S100E

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

13.9 kDa (121aa) confirmed by MALDI-TOF

Additionnal Information

S100A3, S100 calcium binding protein A3, S100E, ATGP1078-10 µg, ATGP1078-20 µg, ATGP1078-50 µg, ATGP1078-100 µg, ATGP1078-250 µg, ATGP1078-500 µg, ATGP1078-1 mg, ATGP1078-10, ATGP1078-20, ATGP1078-50, ATGP1078-100, ATGP1078-250, ATGP1078-500, ATGP1078-1

References & Citations

Fritz G., et al. (1998) Biochim Biophys Acta. 1448 (2) :264-76. ; ; Kizawa K., et al. (2008) J Biol Chem. 283 (8) :5004-13.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 2mM DTT, 0.2M NaCl.

Scientific Category

Signal Transduction

NCBI Accession Number

NP_002951

Uniprot Accession Number

P33764

Species

Human

AA Sequence

MARPLEQAVA AIVCTFQEYA GRCGDKYKLC QAELKELLQK ELATWTPTEF RECDYNKFMS VLDTNKDCEV DFVEYVRSLA CLCLYCHEYF KDCPSEPPCS Q

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