Recombinant human NUDT9 protein

NuDT9 belongs to a superfamily of Nudix hydrolases. It is known to function as a highly specific adenosine diphosphate ribose pyrophosphatase that hydrolyzes ADP ribose to AMP and ribose 5'-phosphate. It has been suggested that NuDT9 may be involved in the regulation of the menstrual cycle and may be related to the proliferation of glandular cells in the human endometrium. Recombinant human NuDT9 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Nudix hydrolase 9, ADP-ribose pyrophosphatase mitochondrial, ADP-ribose diphosphatase, Adenosine diphosphoribose pyrophosphatase, ADPR-Ppase, Nucleoside diphosphate-linked moiety X motif 9, Nudix motif 9, NUDT10

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

36.5 kDa (325aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

Additionnal Information

NUDT9, ADP-ribose pyrophosphatase mitochondrial isoform a., ADP-ribose pyrophosphatase, mitochondrial isoform a., MGC3037, NuDT10, ATGP1062-10 µg, ATGP1062-20 µg, ATGP1062-50 µg, ATGP1062-100 µg, ATGP1062-250 µg, ATGP1062-500 µg, ATGP1062-1 mg, ATGP1062-10, ATGP1062-20, ATGP1062-50, ATGP1062-100, ATGP1062-250, ATGP1062-500, ATGP1062-1

References & Citations

Perraud AL., et al. (2001) Nature. 411 (6837) :595-9. ; ; Perraud AL., et al. (2003) J Biol Chem. 278 (3) :1794-801.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT, 0.1M NaCl.

Scientific Category

Signal Transduction

NCBI Accession Number

NP_076952

Uniprot Accession Number

Q9BW91

Species

Human

AA Sequence

NTNVMSGSN GSKENSHNKA RTSPYPGSKV ERSQVPNEKV GWLVEWQDYK PVEYTAVSVL AGPRWADPQI SESNFSPKFN EKDGHVERKS KNGLYEIENG RPRNPAGRTG LVGRGLLGRW GPNHAADPII TRWKRDSSGN KIMHPVSGKH ILQFVAIKRK DCGEWAIPGG MVDPGEKISA TLKREFGEEA LNSLQKTSAE KREIEEKLHK LFSQDHLVIY KGYVDDPRNT DNAWMETEAV NYHDETGEIM DNLMLEAGDD AGKVKWVDIN DKLKLYASHS QFIKLVAEKR DAHWSEDSEA DCHAL