Recombinant human Prostaglandin E synthase 2/PTGES2 protein

PTGES2 is a membrane-associated prostaglandin E synthase, which catalyzes the conversion of prostaglandin H2 to prostaglandin E2. This protein also has been shown to activate the transcription regulated by a gamma-interferon-activated transcription element. Recombinant human PTGES2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Prostaglandin E synthase 2, hCG_1785478, C9orf15, PGES2, Membrane-associated prostaglandin E synthase-2, Prostaglandin-H (2) E-isomerase

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

23.5 kDa (206aa) confirmed by MALDI-TOF

Additionnal Information

PTGES2, Prostaglandin E synthase 2, hCG_1785478, C9orf15, PGES2, ATGP1059-10 µg, ATGP1059-20 µg, ATGP1059-50 µg, ATGP1059-100 µg, ATGP1059-250 µg, ATGP1059-500 µg, ATGP1059-1 mg, ATGP1059-10, ATGP1059-20, ATGP1059-50, ATGP1059-100, ATGP1059-250, ATGP1059-500, ATGP1059-1

References & Citations

Murakami M., et al. (2003) J Biol Chem. 278 (39) :37937-47. ; ; Meng Q., et al. (2005) J Immunol. 174 (10) :6203-11.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 2mM DTT, 0.2M NaCl, 0.1mM PMSF

Scientific Category

Signal Transduction

NCBI Accession Number

NP_945176

Uniprot Accession Number

Q9H7Z7

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MKAVNEQGKE VTEFGNKYWL MLNEKEAQQV YGGKEARTEE MKWRQWADDW LVHLISPNVY RTPTEALASF DYIVREGKFG AVEGAVAKYM GAAAMYLISK RLKSRHRLQD NVREDLYEAA DKWVAAVGKD RPFMGGQKPN LADLAVYGVL RVMEGLDAFD DLMQHTHIQP WYLRVERAIT EASPAH