Recombinant human SNRPB2 protein
SNRPB2, also known as u2 small nuclear ribonucleoprotein B, belongs to the RRM u1 A/B family. This protein associates with stem loop IV of u2 small nuclear ribonucleoprotein (u2 snRNP) in the presence of snRNP-A. It may play a role in pre-mRNA splicing. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding the same protein have been found for this gene. Recombinant human SNRPB2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Product Specifications
Product Name Alternative
U2 small nuclear ribonucleoprotein B, u2 snRNP B
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
27.6 kDa (245aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Guo JX., et al. (2001) Biophys J. 81 (2) :630-42; ; Price S.R., et al. (1998) Nature.394:645-650
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 40% glycerol, 0.1M NaCl
Scientific Category
Immunology
NCBI Accession Number
NP_003083
Uniprot Accession Number
P08579
Species
Human
AA Sequence
Frequently Asked Questions
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