Recombinant human S100A16 protein
S100 calcium binding protein A16, also known S100A16, is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. Intracellularly, S100A16 is both nuclear and cytoplasmic and apparently exists as a homodimer, trimer and tetramer. It contains two EF-hand motifs with only one high-affinity Ca-binding site and apparently undergoes phosphorylation at Ser103. Recombinant human S100A16 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
S100 calcium binding protein A16, AAG13, S100F
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
13.9 kDa (123aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Marenholz I., et al. (2004) Biochem Biophys Res Commun. 313 (2) :237-44.; ; Sturchler E., et al. (2006) J Biol Chem. 281 (50) :38905-17.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 40% glycerol,0.2M NaCl
Scientific Category
Cell Cycle
NCBI Accession Number
NP_525127
Uniprot Accession Number
Q96FQ6
Species
Human
AA Sequence
MGSSHHHHHH SSGLVPRGSH MSDCYTELEK AVIVLVENFY KYVSKYSLVK NKISKSSFRE MLQKELNHML SDTGNRKAAD KLIQNLDANH DGRISFDEYW TLIGGITGPI AKLIHEQEQQ SSS
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