Recombinant human Annexin A13/ANXA13 protein
Annexin A13, also known as ANXA13, is a member of the annexin protein family. Members of the annexin family play a role in cytoskeletal interactions, phospholipase inhibition, regulation of cellular growth, and intracellular signal transduction pathways. ANXA13 is considered the original progenitor of the 12 members of vertebrate annexins. The expression of ANXA13 is highly tissue-specific, being expressed only in intestinal and kidney epithelial cells. This expression is associated with a highly differentiated intracellular transport function. Recombinant human ANXA13 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Annexin XIII, Annexin-13, Intestine-specific annexin, ISA, ANX13
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
37.5 kDa (336aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Smith P D., et al. (1994) Trends Genet. 10:241-246.; ; Lqlesias J M., et al. (2002) Mol Biol Evol. 19:133-140.
Other References
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 30% glycerol, 0.1M NaCl, 1mM EDTA
Scientific Category
Adhesion & Movement
NCBI Accession Number
NP_004297
Uniprot Accession Number
P27216
Species
Human
AA Sequence
Frequently Asked Questions
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