Recombinant human Annexin A13/ANXA13 protein

Annexin A13, also known as ANXA13, is a member of the annexin protein family. Members of the annexin family play a role in cytoskeletal interactions, phospholipase inhibition, regulation of cellular growth, and intracellular signal transduction pathways. ANXA13 is considered the original progenitor of the 12 members of vertebrate annexins. The expression of ANXA13 is highly tissue-specific, being expressed only in intestinal and kidney epithelial cells. This expression is associated with a highly differentiated intracellular transport function. Recombinant human ANXA13 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Annexin XIII, Annexin-13, Intestine-specific annexin, ISA, ANX13

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

37.5 kDa (336aa) confirmed by MALDI-TOF

Additionnal Information

Annexin A13, Annexin A13, ANX13, ISA, Annexin-13, ATGP1014-10 µg, ATGP1014-20 µg, ATGP1014-50 µg, ATGP1014-100 µg, ATGP1014-250 µg, ATGP1014-500 µg, ATGP1014-1 mg, ATGP1014-10, ATGP1014-20, ATGP1014-50, ATGP1014-100, ATGP1014-250, ATGP1014-500, ATGP1014-1

References & Citations

Smith P D., et al. (1994) Trends Genet. 10:241-246.; ; Lqlesias J M., et al. (2002) Mol Biol Evol. 19:133-140.

Other References

Sakamoto N et al., Anti-annexin A4 antibody as a biomarker for desquamative interstitial pneumonia. (J Autoimmun. 2025) {https://pubmed.ncbi.nlm.nih.gov/40156961/}

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 30% glycerol, 0.1M NaCl, 1mM EDTA

Scientific Category

Adhesion & Movement

NCBI Accession Number

NP_004297

Uniprot Accession Number

P27216

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGNRHAKASS PQGFDVDRDA KKLNKACKGM GTNEAAIIEI LSGRTSDERQ QIKQKYKATY GKELEEVLKS ELSGNFEKTA LALLDRPSEY AARQLQKAMK GLGTDESVLI EVLCTRTNKE IIAIKEAYQR LFDRSLESDV KGDTSGNLKK ILVSLLQANR NEGDDVDKDL AGQDAKDLYD AGEGRWGTDE LAFNEVLAKR SYKQLRATFQ AYQILIGKDI EEAIEEETSG DLQKAYLTLV RCAQDCEDYF AERLYKSMKG AGTDEETLIR IVVTRAEVDL QGIKAKFQEK YQKSLSDMVR SDTSGDFRKL LVALLH