Recombinant human SNRPG protein

Small nuclear ribonucleoprotein polypeptide G, also known as SNRPG, belongs to the snRNP Sm proteins family. There are at least seven isoforms, B/B, E, F, G, D1, D2, and D3. This class of common proteins plays an essential role in the biogenesis of the snRNPs. The genes encoding human Sm G map to chromosomes 2. In addition, these proteins represent the major targets for the so-called anti-Sm auto-antibodies which are diagnostic for systemic lupus erythematosus (SLE) . One class of these autoantibodies reacts specifically with native Sm E-F-G complexes. Recombinant human SNRPG protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Small nuclear ribonucleoprotein polypeptide G, Sm-G, SMG

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

10.6 kDa (96aa) confirmed by MALDI-TOF

Additionnal Information

SNRPG, Small nuclear ribonucleoprotein polypeptide G, Sm-G, SMG, ATGP1011-10 µg, ATGP1011-20 µg, ATGP1011-50 µg, ATGP1011-100 µg, ATGP1011-250 µg, ATGP1011-500 µg, ATGP1011-1 mg, ATGP1011-10, ATGP1011-20, ATGP1011-50, ATGP1011-100, ATGP1011-250, ATGP1011-500, ATGP1011-1