Recombinant human AIF-1/Iba1 protein

AIF1 (Allograft inflammatory factor 1) is induced by cytokines and interferon. This protein is thought to be involved in negative regulation of growth of vascular smooth muscle cells, which contributes to the anti-inflammatory response to vessel wall trauma. AIF1 is a cytoplasm, calcium-binding protein whose expression in transplanted human hearts correlates with rejection and development of coronary artery vasculopathy (CAV) . Recombinant human AIF1, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Allograft inflammatory factor 1, AIF-1, IBA1, IRT-1, IRT1

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

18.9 kDa (167aa) confirmed by MALDI-TOF

Additionnal Information

AIF1, Iba1, Allograft inflammatory factor 1, AIF-1, IBA1, IRT-1, IRT1, ATGP1006-10 µg, ATGP1006-20 µg, ATGP1006-50 µg, ATGP1006-100 µg, ATGP1006-250 µg, ATGP1006-500 µg, ATGP1006-1 mg, ATGP1006-10, ATGP1006-20, ATGP1006-50, ATGP1006-100, ATGP1006-250, ATGP1006-500, ATGP1006-1

References & Citations

Kelemen S.E., et al (2005) Am. J. Pathol. 167:619-626; ; Schulze J.O., et al. (2008) FEBS J. 275:4627-4640

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 20% glycerol, 200 mM NaCl

Scientific Category

Immunology

NCBI Accession Number

NP_001614

Uniprot Accession Number

P55008

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MSQTRDLQGG KAFGLLKAQQ EERLDEINKQ FLDDPKYSSD EDLPSKLEGF KEKYMEFDLN GNGDIDIMSL KRMLEKLGVP KTHLELKKLI GEVSSGSGET FSYPDFLRMM LGKRSAILKM ILMYEEKARE KEKPTGPPAK KAISELP