Recombinant human LMP2/PSMB9 protein
PSMB9, also known as proteasome subunit beta type-9, is a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This protein is located in the class II region of the MHC (major histocompatibility complex) . Expression of this protein is induced by gamma interferon and this gene product replaces catalytic subunit 1 (proteasome beta 6 subunit) in the immunoproteasome. Recombinant human PSMB9 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Product Specifications
Product Name Alternative
Proteasome subunit beta type-9, LMP2, PSMB6i, RING12
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
23.5 kDa (220aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Jia M., et al, (2010) Proteomics Clin Appl. 4 (10-11) :816-28 ; ; Kelly A., et al, (1991) Nature 353 (6345) :667-8.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 50 mM NaCl
Scientific Category
Cell Cycle
NCBI Accession Number
NP_002791.1
Uniprot Accession Number
P28065
Species
Human
AA Sequence
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