Recombinant human S100A7 protein

S100A7, also known as Psoriasin, belongs to the S-100 family of calcium binding proteins and is secreted via a non-classical secretory pathway into the cytoplasm. It is thought to function in the regulation of many cellular processes, including the cell cycle, cell progression and cellular differentiation. It contains two EF-hand domains and is highly upregulated in psoriatic epidermis, as well as in bladder squamous cell carcinoma and breast cancer tissue, suggesting a possible role in carcinogenesis. Recombinant human S100A7 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Product Specifications

Product Name Alternative

S100 calcium binding protein A7, S100A7c, Psoriasin

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

13.6 kDa (121aa) confirmed by MALDI-TOF

Additionnal Information

S100A7, S100 calcium binding protein A7, S100A7c, Psoriasin, ATGP0991-10 µg, ATGP0991-20 µg, ATGP0991-50 µg, ATGP0991-100 µg, ATGP0991-250 µg, ATGP0991-500 µg, ATGP0991-1 mg, ATGP0991-10, ATGP0991-20, ATGP0991-50, ATGP0991-100, ATGP0991-250, ATGP0991-500, ATGP0991-1

References & Citations

Celis J.E., et al. (1998) . Structure., 6: 477-489; ; Martinsson H., et al. (2005) . Exp. Dermatol., 14: 161-168.

Other References

Jung SH, et al. Integrative proteomic profiling of protein activity and interactions using protein arrays. (Mol Cell Proteomics. 2012) {https://pubmed.ncbi.nlm.nih.gov/22843993/}; ; Jung SH, et al. Identification of transglutaminase 2 kinase substrates using a novel on-chip activity assay. (Biosens Bioelectron. 2016) {https://pubmed.ncbi.nlm.nih.gov/27040940/}; ; Jung SH, et al. Systematic investigation of protein kinase A substrate proteins using on-chip protein kinase kinetic profiling. (Analyst. 2017) {https://pubmed.ncbi.nlm.nih.gov/28536714/}