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Recombinant human Galectin-7/LGALS7 protein

LGALS7, also known as galectin7, is a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Members of this family have been implicated in a variety of functions, including growth regulation, cell adhesion, migration, neoplastic transformation, and immune responses. It is expressed mainly in stratified squamous epithelium, LGALS7 protein is activated by p53 and repressed by retinoic acid. It is a pro-apoptotic protein that functions intracellularly upstream of JNK activation and cytochrome c release. Recombinant human LGALS7 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Galectin7, GAL7, LGALS7A, HKL-14, PI7, p53-induced gene 1 protein, TP53I1, PIG1, LGALS7A

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

17.2 kDa (156aa) confirmed by MALDI-TOF

Additionnal Information

Galectin7, Galectin7, GAL7, LGALS7A, ATGP0986-10 µg, ATGP0986-20 µg, ATGP0986-50 µg, ATGP0986-100 µg, ATGP0986-250 µg, ATGP0986-500 µg, ATGP0986-1 mg, ATGP0986-10, ATGP0986-20, ATGP0986-50, ATGP0986-100, ATGP0986-250, ATGP0986-500, ATGP0986-1

References & Citations

Magnaldo T., et al. (1995) Dev Biol. 168 (2) :259-71. ; ; Magnaldo T., et al. (1998) Differentiation. 63 (3) :159-68.

Other References

Fabregat FN et al., Structure of the Lipopolysaccharide from Paenalcaligenes hominis: A Chemical Perspective on Immune Recognition. (JACS Au. 2025) {https://doi.org/10.1021/jacsau.5c00441}

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT

Scientific Category

Cancer

NCBI Accession Number

NP_002298

Uniprot Accession Number

P47929

Species

Human

AA Sequence

MSNVPHKSSL PEGIRPGTVL RIRGLVPPNA SRFHVNLLCG EEQGSDAALH FNPRLDTSEV VFNSKEQGSW GREERGPGVP FQRGQPFEVL IIASDDGFKA VVGDAQYHHF RHRLPLARVR LVEVGGDVQL DSVRIF

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