What is the catalog number for Recombinant human DECR1 protein?

The catalog number for Recombinant human DECR1 protein is ATGP0984-100.

What sizes are available for Recombinant human DECR1 protein?

Recombinant human DECR1 protein is available in the following size(s): 100 µg.

Is Recombinant human DECR1 protein in stock?

Recombinant human DECR1 protein is currently made to order / not held in immediate stock. Contact us for lead time.

Recombinant human DECR1 protein

DECR1 is a mitochondrial protein that exists as a homotetramer and belongs to the family of short-chain dehydrogenases/reductases. It functions as an auxiliary enzyme of beta-oxidation andt participates in the metabolism of unsaturated fatty enoyl-CoA esters. Specifically, DECR1 uses NADP+ to catalyze the reduction of 2, 4-dienoyl-CoA to yield trans-3-enoyl-CoA, which can then be used as an intermediate in the Krebs cycle. Additionally, DECR1 is thought to function as a tumor suppressor, possibly downregulating the expression of Neu and slowing the rate of tumorigenesis. Recombinant human DECR1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

24-dienoyl-CoA reductase mitochondrial, 2,4-dienoyl-CoA reductase, mitochondrial, DECR, NADPH, SDR18C1

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

34.4 kDa (322aa) confirmed by MALDI-TOF

Additionnal Information

DECR1, 24-dienoyl-CoA reductase mitochondrial, 2,4-dienoyl-CoA reductase, mitochondrial, DECR, NADPH, SDR18C1, ATGP0984-10 µg, ATGP0984-20 µg, ATGP0984-50 µg, ATGP0984-100 µg, ATGP0984-250 µg, ATGP0984-500 µg, ATGP0984-1 mg, ATGP0984-10, ATGP0984-20, ATGP0984-50, ATGP0984-100, ATGP0984-250, ATGP0984-500, ATGP0984-1

References & Citations

Koivuranta KT., et al. (1994) Biochem J. 304 (3) :787-92. ; ; Roe CR., et al. (1990) J Clin Invest. 85 (5) :1703-7.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT

Scientific Category

Cancer

NCBI Accession Number

NP_001350

Uniprot Accession Number

Q16698

Species

Human

AA Sequence

NTEALQSKF FSPLQKAMLP PNSFQGKVAF ITGGGTGLGK GMTTLLSSLG AQCVIASRKM DVLKATAEQI SSQTGNKVHA IQCDVRDPDM VQNTVSELIK VAGHPNIVIN NAAGNFISPT ERLSPNAWKT ITDIVLNGTA FVTLEIGKQL IKAQKGAAFL SITTIYAETG SGFVVPSASA KAGVEAMSKS LAAEWGKYGM RFNVIQPGPI KTKGAFSRLD PTGTFEKEMI GRIPCGRLGT VEELANLAAF LCSDYASWIN GAVIKFDGGE EVLISGEFND LRKVTKEQWD TIEELIRKTK GS