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Recombinant human ALDOC protein

ALDOC, also known as aldolase C, is a member of the class I fructose-biphosphate aldolase family. This protein is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose-1, 6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehydes respectively. It is expressed specifically in the hippocampus and Purkinje cells of the brain. Recombinant human ALDOC protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Aldolase C fructose-bisphosphate., Aldolase C, fructose-bisphosphate., ALDC

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

41.6 kDa (384aa) confirmed by MALDI-TOF

Additionnal Information

ALDOC, Aldolase C fructose-bisphosphate., Aldolase C, fructose-bisphosphate., ALDC, ATGP0980-10 µg, ATGP0980-20 µg, ATGP0980-50 µg, ATGP0980-100 µg, ATGP0980-250 µg, ATGP0980-500 µg, ATGP0980-1 mg, ATGP0980-10, ATGP0980-20, ATGP0980-50, ATGP0980-100, ATGP0980-250, ATGP0980-500, ATGP0980-1

References & Citations

Wang CF., et al. (2007) Anim Genet. 38 (3) :203-10. ; ; Arakaki TL., et al. (2004) Protein Sci. 13 (12) :3077-84.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 2mM DTT, 0.1M NaCl.

Scientific Category

Cancer

NCBI Accession Number

NP_005156

Uniprot Accession Number

P09972

Species

Human

AA Sequence

MPHSYPALSA EQKKELSDIA LRIVAPGKGI LAADESVGSM AKRLSQIGVE NTEENRRLYR QVLFSADDRV KKCIGGVIFF HETLYQKDDN GVPFVRTIQD KGIVVGIKVD KGVVPLAGTD GETTTQGLDG LSERCAQYKK DGADFAKWRC VLKISERTPS ALAILENANV LARYASICQQ NGIVPIVEPE ILPDGDHDLK RCQYVTEKVL AAVYKALSDH HVYLEGTLLK PNMVTPGHAC PIKYTPEEIA MATVTALRRT VPPAVPGVTF LSGGQSEEEA SFNLNAINRC PLPRPWALTF SYGRALQASA LNAWRGQRDN AGAATEEFIK RAEVNGLAAQ GKYEGSGEDG GAAAQSLYIA NHAY
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