Recombinant human PDCD6 protein
Programmed cell death 6, also known as PDCD6, is calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant. Recombinant human PDCD6 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Product Specifications
Product Name Alternative
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
24.0 kDa (211aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Okumura M., et al. (2009) Biochem. Biophys. Res. Commun. 386:237-241.; ; Suzuki H., et al. (2008), Structure 16:1562-1573
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 10 mM Sodium Citrate buffer (pH 3.5) containing 40% glycerol
Scientific Category
Apoptosis
NCBI Accession Number
NP_037364
Uniprot Accession Number
O75340
Species
Human
AA Sequence
Explore Other Products
Browse additional items from our catalog
ZNF297B Overexpression Lysate (Native) - (Dry Ice)
FRA8D sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human)
