Recombinant human ZCCHC17 protein
ZCCHC17, also known as pNO40 or PS1D, is a 241 amino acid protein that interacts with both Pinin and the 60S ribosomal subunit. Localizing to nucleolus, ZCCHC17 is ubiquitously expressed and has been suggested to play a role in ribosome maturation and biogenesis. Recombinant human ZCCHC17 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Nucleolar protein of 40 kDa, HSPC251, pNO40, PS1D, RP11-266K22.1, zinc finger CCHC domain containing 17, putative S1 RNA-binding domain protein
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
30 kDa (264aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
Additionnal Information
References & Citations
Chang W.-L., et al. (2003) Biochem. Biophys. Res. Commun. 307:569-577; ; Betarbet, R., et al. (2008) Neurobiol. Dis. 31: 309-315
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 20% glycerol, 0.1M NaCl, 0.1mM PMSF
Scientific Category
Metabolism
NCBI Accession Number
NP_057589
Uniprot Accession Number
Q9NP64
Species
Human
AA Sequence
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