Recombinant human RGS2 protein

RGS2, also known as G0S8, is a RGS family member and regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. This protein inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Recombinant human RGS2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Regulator of G-protein signaling 2 24kDa, G0S8

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

26.5 kDa (231aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

Additionnal Information

RGS2, Regulator of G-protein signaling 2 24kDa, G0S8, ATGP0975-10 µg, ATGP0975-20 µg, ATGP0975-50 µg, ATGP0975-100 µg, ATGP0975-250 µg, ATGP0975-500 µg, ATGP0975-1 mg, ATGP0975-10, ATGP0975-20, ATGP0975-50, ATGP0975-100, ATGP0975-250, ATGP0975-500, ATGP0975-1

References & Citations

Tang KM., et al. (2003) Nat Med. 9 (12) :1506-12. ; ; Santos de Araujo RM., et al. (2007) Cell Biochem Funct. 25 (6) :753-8.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 2mM DTT, 0.1M NaCl.

Scientific Category

Signal Transduction

NCBI Accession Number

NP_002914.1

Uniprot Accession Number

P41220

Species

Human

AA Sequence

QSAMFLAVQ HDCRPMDKSA GSGHKSEEKR EKMKRTLLKD WKTRLSYFLQ NSSTPGKPKT GKKSKQQAFI KPSPEEAQLW SEAFDELLAS KYGLAAFRAF LKSEFCEENI EFWLACEDFK KTKSPQKLSS KARKIYTDFI EKEAPKEINI DFQTKTLIAQ NIQEATSGCF TTAQKRVYSL MENNSYPRFL ESEFYQDLCK KPQITTEPHA T