Recombinant human S100A14 protein
S100A14 is a member of a subfamily of proteins related by EF-hand Ca2+ binding protein superfamily. The extracellular functions of the S-100 family may include the ability to enhance neurite outgrowth, involvement in inflammation, and motility of tumor cells. S100A14 contains 2 EF-hand Ca2+-binding domains, a myristoylation motif, a glycosylation site, and several potential protein kinase phosphorylation sites. It is expressed at high level in the colon and at moderate level in the thymus, kidney, liver, small intestine, and lung. Recombinant human S100A14 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
S100 calcium binding protein A14, BCMP84, S100A15
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
13.8 kDa (124aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Wright NT., et al. (2005) J Mol Biol. 353 (2) :410-26. ; ; Zimmer DB., et al. (2005) Cell Mol Biol. 51 (2) :201-14.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 2mM DTT
Scientific Category
Cancer
NCBI Accession Number
NP_065723
Uniprot Accession Number
Q9HCY8
Species
Human
AA Sequence
MGSSHHHHHH SSGLVPRGSH MGQCRSANAE DAQEFSDVER AIETLIKNFH QYSVEGGKET LTPSELRDLV TQQLPHLMPS NCGLEEKIAN LGSCNDSKLE FRSFWELIGE AAKSVKLERP VRGH
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