Recombinant human S100A10 protein
S100 calcium binding protein A10, also known S100A10, is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100A10 is primarily found in mast cells as heterotetrameric complexes that are present intracellularly at the plasma membrane or on the extracellular cell surface. Extracellular S100A10 is a key plasminogen receptor that plays an important role in cellular plasmin production and cellular invasiveness. Recombinant human S100A10 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
S100 calcium binding protein A10, 42C, ANX2L, ANX2LG, CAL1, CLP11 GP11, p10, P11
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
13.3 kDa (117aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
EI Rifai W., et al. (2000) Cancer Res. 62:6823-6826.; ; Gattaz W F., et al. (2000) Schizo Res. 43:91-5.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 40% glycerol,0.1M NaCl, 0.1mM PMSF
Scientific Category
Signal Transduction
NCBI Accession Number
NP_002957.1
Uniprot Accession Number
P60903
Species
Human
AA Sequence
MPSQMEHAME TMMFTFHKFA GDKGYLTKED LRVLMEKEFP GFLENQKDPL AVDKIMKDLD QCRDGKVGFQ SFFSLIAGLT IACNDYFVVH MKQKGKK
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