Recombinant human MSRB3 protein

Methionine sulfoxide reductase B3, also known as MSRB3, belongs to the methionine sulfoxide reductases (MSR) family proteins. MSRs are thought to protect against reactive oxygen species-induced oxidative damage in many organs, including the most environmentally exposed organ, human skin. MSRB3 plays an important role in cold tolerance by eliminating MetO and ROS that accumulate at the ER during cold acclimation. Recombinant human MSRB3 protein, fused to His-tag at C-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Methionine sulfoxide reductase B3

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

19 kDa (174aa) confirmed by MALDI-TOF

Additionnal Information

MSRB3, Methionine sulfoxide reductase B3, ATGP0951-10 µg, ATGP0951-20 µg, ATGP0951-50 µg, ATGP0951-100 µg, ATGP0951-250 µg, ATGP0951-500 µg, ATGP0951-1 mg, ATGP0951-10, ATGP0951-20, ATGP0951-50, ATGP0951-100, ATGP0951-250, ATGP0951-500, ATGP0951-1

References & Citations

Taunqiaruwinai WM., et al. (2009) Am J Dermatopathol. 31 (5) :427-31-7.; ; Kwon SJ., et al. (2007) Plant Cell Physiol. 48 (12) :1713-23.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 0.1mM PMSF

Scientific Category

Metabolism

NCBI Accession Number

NP_001026849

Uniprot Accession Number

Q8IXL7

Species

Human

AA Sequence

MCGLPSGSCR DKKNCKVVFS QQELRKRLTP LQYHVTQEKG TESAFEGEYT HHKDPGIYKC VVCGTPLFKS ETKFDSGSGW PSFHDVINSE AITFTDDFSY GMHRVETSCS QCGAHLGHIF DDGPRPTGKR YCINSAALSF TPADSSGTAE GGSGVASPAQ ADKAELLEHH HHHH